{"product_id":"neuropathology-and-genetics-of-dementia-advances-in-experimental-medicine-and-biology-volume-487-0306465582","title":"Neuropathology and Genetics of Dementia (Advances in Experimental Medicine and Biology Volume 487)","description":"\u003cp\u003e\u003cstrong\u003eISBN:\u003c\/strong\u003e 0306465582\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eAuthor:\u003c\/strong\u003e Tolnay, Markus\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eCondition:\u003c\/strong\u003e New\u003c\/p\u003e\u003cp\u003ethese \"tauopathies\" are reviewed by Delacourte. Therecentdiscoverythatmutationsofthetaugenearecausativeforfamilial formsoffrontotemporaldementiaandParkinsonism(FTDP-17)broughtthe \"taupathway\"and the\"tauopathies\"tothecentrestage.Thisextraordinary breakthroughwillbecoveredbySpillantiniandGoedert.Thereisincreasing evidence that argyrophilic grain disease is much more frequent in older patients than previously thought. Tolnay et al. are reviewing recent contributionstothepathologyofthislate-onsetdementingdisorderinwhich ofamyloidbetadeposits,isalmost taupathology,inthealmosttotalabsence exclusivelyrestricted to the limbic lobe and the amygdala. Schultzet al. report an intriguing age-related progression of neuronal and glial tau pathologyinbaboonsthusrenderingthe baboonapotentialprimatemodel forage-relatedhuman\"tauopathies\". Gotzetal. introducetransgenicmice expressingmutated human tau as valuable animal models for reproducing formationofneuro-andglialfibrillarylesions.\u003c\/p\u003e","brand":"Mia Karts","offers":[{"title":"Default Title","offer_id":51735345561888,"sku":"NEW0306465582","price":189.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0980\/7426\/3840\/files\/61D6nBzCFvL.jpg?v=1779482546","url":"https:\/\/miakarts.com\/products\/neuropathology-and-genetics-of-dementia-advances-in-experimental-medicine-and-biology-volume-487-0306465582","provider":"Miakarts Books","version":"1.0","type":"link"}