{"product_id":"synthesis-and-biological-testing-of-1-adamantyl-derivatives-different-synthetic-methods-and-biological-evaluation-of-adamantane-containing-derivatives-3639246705","title":"Synthesis and biological testing of 1-adamantyl derivatives: Different synthetic methods and biological evaluation of adamantane containing derivatives","description":"\u003cp\u003e\u003cstrong\u003eISBN:\u003c\/strong\u003e 3639246705\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eAuthor:\u003c\/strong\u003e AlAbdullah, Ebtehal\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eCondition:\u003c\/strong\u003e New\u003c\/p\u003e\u003cp\u003eSeveral adamantane derivatives have long been known for diverse biological properties, mainly as antiviral, antibacterial, antifungal and anti-inflammatory agents. adamantyl derivatives were recently reported to possess 11-HSD1 inhibitory activities. In addition, 1,2,4-triazole and 1,3,4-thiadiazole were reported to constitute the pharmacologically active moiety of several compounds. On these bases new series of 1-adamantyl derivatives, in which the adamantyl moiety was attached to 1,2,4-triazole, 1,2,4-triazolo[3,4-b][1,3,4]thiadiazole or 1,3,4-thiadiazole nucleus, have been synthesized as potential bioactive agents All the synthesized compounds were tested for their in vitro growth inhibitory activity against a panel of standard strains of pathogenic microorganism including Gram-positive bacteria, Gram-negative bacteria and the yeast-like pathogenic fungus Candida albicans. In addition, the acute anti-inflammatory activity of a representative compounds was determined in vivo following the carrageenan-induced paw oedema method in rats.\u003c\/p\u003e","brand":"Mia Karts","offers":[{"title":"Default Title","offer_id":51929836224800,"sku":"NEW3639246705","price":110.4,"currency_code":"USD","in_stock":false}],"url":"https:\/\/miakarts.com\/products\/synthesis-and-biological-testing-of-1-adamantyl-derivatives-different-synthetic-methods-and-biological-evaluation-of-adamantane-containing-derivatives-3639246705","provider":"Miakarts Books","version":"1.0","type":"link"}